Types of inflammation

Local manifestations of inflammation depends on the cause of the particular tissue involved

These manifestations can range from swelling in the formation of the exudates to excess formation or ulceration.

The acute inflammatory response involves production of exudates that vary in term of fluid/ plasma proteins and cellular debris

• Serous
• Hemorrhagic
• Fibronous
• Membranes or purulent exudates

Inflammatory exudates often composed of a combination of these types

Inflammation – capillary dilatation, fluid exudates formation, neutrophil migration

Suppuration – development of suppurative or purulent exudates containing degraded neutrophils and tissue debris

Abscess formation – walling off of the area of purulent (pus) exudates to form an abscess

Acute	Process typically lasts from a few minutes to a few days Usually resolves with little or no scarring Appears with both local and systemic manifestations – 8-10 days
Chronic	May last for weeks, months or years (usually has exacerbations and remission). Low grade persistent irritant produces fewer systemic symptoms. Most symptoms are localized in this case. Granuloma formation is usually associated with a foreign body. A dense membrane of connective tissue encapsulates the lesion. – more than 2 weeks

Chronic Inflammation – Granuloma formation Foreign body giant cell

The numerous nuclei are randomly arranged in the cytoplasm of the cell, a granulomatous lesion is a distinctive form of chronic inflammation, typically a small 1-2 mm lesion in which there are a massing of macrophage surrounded by lymphocytes

Takes place in about the same way mo matter what the stimulus

Area becomes congested causing redness and warmth

Cellular components - Granulocytes, monocytes

All of these leukocytes can carry out phagocytosis

Circulate in the blood stream and are stimulated by inflammation to an area of injury

Basophil – allergy

Monocyte biggest white cells